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The presented MR approach might become a valuable tool to study (micro)-vascular pathophysiology. Heraldic signs of the 2nd Medical School of Charles University in Prague

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from the invasive rock pool mosquito, Ochlerotatus japonicus japonicus. Resummed memory kernels in generalized system-bath master equations. In a previous deuterium NMR study conducted on a liquid crystalline (LC) polymer with laterally attached book-shaped molecules as the mesogenic moiety, we have revealed a biaxial nematic phase below the conventional uniaxial nematic phase (Phys.

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The physiological changes occur during normal pregnancy, such as increase blood volume and cardiac output (CO) may be detrimental in PH patients. Size-dependent magnetic properties of CoFe2O4 nanoparticles prepared in polyol.

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The Clinical Laboratory Improvement Amendments of 1988--analysis. Influence of ultrasonic activation on photodynamic therapy over root canal system infected with Enterococcus faecalis--an in vitro study.

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Endoscopic variceal sclerotherapy as primary treatment for bleeding esophageal varices. Conjunctival biopsy: a useful procedure for the diagnosis of sarcoidosis

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Interleukin-1 (IL-1) plays an important role in the pathogenesis of osteoarthritis (OA) either directly or through the stimulation of catabolic factors, such as nitric oxide (NO). The specific objectives were to examine the efficacy of interventions to improve heart failure self-care (self-maintenance and self-management behaviours) and patient-related factors such as knowledge about heart failure, self-efficacy for heart failure self-care (confidence) and beliefs regarding heart failure self-care. Ataxia and tremors are relatively common manifestations of typhoid fever in Papua New Guinea. The minimum-energy conformation was attained through an extended hard-sphere exo-anomeric effect (HSEA) approach.

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The present study investigated the effects of purified recombinant murine IL-4 on early hemopoetic progenitors in methylcellulose culture. Evidence accumulated over the past two decades indicates that HCV has metabolic associations, in particular insulin resistance and diabetes mellitus. Analyses currently supported include quantification of gene expression for messenger and small RNA sequencing, estimation of DNA methylation (i.e., reduced bisulfite sequencing and whole genome methyl-seq), or the detection of pathogens in sequenced data. The retinoblastoma tumor suppressor (Rb) pathway is mutated in most, if not all human tumors. On 2 occasions, 69 patients with work-related stress and 62 healthy participants completed self-report instruments to measure alexithymia (20-item Toronto Alexithymia Scale), burnout complaints (Maslach Burnout Inventory) and general distress complaints (Depression Anxiety Stress Scales, Checklist Individual Strength).

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Baseline levels of autophagy detected in cultured undifferentiated hESC were increased or decreased in the presence of rapamycin and wortmannin, respectively. The feasibility and biomechanical properties of this design were also evaluated. Sex differences in cortical thickness and their possible genetic and sex hormonal underpinnings.

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In rats receiving bilateral femoral arteries ligation (day 0), repeated oral administration of the prostacyclin derivative beraprost sodium (50 microg/kg, b.i.d.) from day 1 to day 5 resulted in a significant prolongation in walking time in rotarod walking exercise performed on day 5. This study investigates longitudinal changes in SRH and examines its sensitivity to changes in chronic conditions and functioning among people aged 90 and older. A novel mutation in the CAG triplet region of exon 1 of androgen receptor gene causes complete androgen insensitivity syndrome in a large kindred. The ability to produce large volumes of endothelium from embryonic stem cells could provide a potential therapeutic modality for vascular injury. Sequencing projects suggest the existence of certain classes of regulators, but experimental verification is needed.

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Inoculation of swine with foot-and-mouth disease SAP-mutant virus induces early protection against disease. In this prospective study, duplex Doppler ultrasound was used in 95 consecutive patients with solid breast masses to evaluate the presence of neovascular flow.

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Recent technological advances in experimental molecular genetics have provided an opportunity for determining the function of any gene including those which are important in different epithelia. Carbazole, carbazoles with monomethyl or dimethyls substituted on different positions (C(1)-carbazoles or C(2)-carbazoles), and benzocarbazoles, as toxic and mutagenic components of petroleum and creosote contamination, were biodegradable by an isolated bacterial strain Pseudomonas sp. A peptidomimetic siRNA transfection reagent for highly effective gene silencing.

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Profilin-mediated INF2 inhibition is relieved by an anti-N-terminal antibody for INF2 that blocks the DID/DAD interaction. Black grandchildren assigned grandparents significantly more favorable ratings for teaching and overall success, whereas Anglo grandchildren assigned their grandparents higher scores for coping with difficulty, managing frustration, and meeting information needs. The experimental mice were forced to inhale the bitumen fume at different exposure level (55 mg/m(3), 165 mg/m(3)) and in different time (30 days, 60 days). Structural determination and packing analysis of a cholesteryl caprate/cholesteryl laurate solid solution.

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Temperature induced stress influence on biodiesel productivity during mixotrophic microalgae cultivation with wastewater. The causes of megaloblastic erythropoiesis incompetence (slow rate, hemolytic component, secondary sideroachresia) are discussed. Nitrate reduction, nitrous oxide formation, and anaerobic ammonia oxidation to nitrite in the gut of soil-feeding termites (Cubitermes and Ophiotermes spp.). Several simulation-based possibilities for training flexible optical intubation have been developed, ranging from non-anatomical phantoms to high-fidelity virtual reality simulators. To evaluate the success of adjustable suture (AS) and nonadjustable suture (NAS) strabismus surgery in primary procedures and reoperations.

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Modules define themselves by spatial sequestration, chemical specificity and a characteristic time domain within which their function proceeds. Surprisingly, the local circular dichroism spectra do not display the excitonic shape of spectra obtained for macroscopic suspensions, but the latter can be produced by superposition of two local spectra of opposite sign. Hypersensitivity reactions to multiple drugs during the course of hairy cell leukemia treated with 2-chlorodeoxyadenosine A novel real-time 6DOF head motion correction technique based on wireless NMR probes is demonstrated in high resolution imaging at 7 Tesla. Changes in autophagy proteins in a rat model of spinal cord injury.

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Long-term oncologic outcomes of laparoscopic versus open partial nephrectomy. Clinicians now have the therapies and outcome tools to implement treat-to-target strategies aimed at achieving and maintaining adequate function and control of symptoms in spondyloarthritis and psoriatic arthritis. In the latter step, the newly identified transcriptional factor Nanog functions in maintaining pluripotency in cooperation with other key gene Oct4.

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We conducted a prospective study to investigate AMH and INSL3 plasma levels in 3 groups of women with polycystic ovary syndrome (PCOS) classified according to menstrual cyclicity pattern and their relationship with ovarian morphology and hormonal levels. The objectives of the study were to evaluate the effect of selected antimicrobial agents on the shelf life of osmotically pretreated gilthead seabream and to establish reliable kinetic equations for shelf-life determination validated in dynamic conditions. Epithelial-mesenchymal transition (EMT) is a key developmental process and has also been implicated in cancer metastasis and therapeutic resistance in recent years.

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In the report case the authors hypothesized a multifactorial background on a genetic basis. Surprisingly, the expression of MYB factors known to regulate GS biosynthesis genes was not altered in myc234, suggesting that MYC2/MYC3/MYC4 are necessary for direct transcriptional activation of GS biosynthesis genes. Grb2 immunoprecipitation from IRS1-transfected and insulin-treated cells demonstrated an increased coimmunoprecipitation of Syp and the p85 regulatory subunit of the phosphatidylinositol 3-kinase.

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The immune system may play an important role in pathophysiology of POR by dysfunctions of cytokines and the growth factor network, and the presence of ovarian auto-antibodies. Microalbuminuria is associated with decreased reversal to normoglycemia and increased progression to diabetes. The professional self-concepts of nursing undergraduates and their perceptions of influential forces. Demonstrating the value in nursing: an interview with Linda McGillis Hall.

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In this case series of pseudophakic, aphakic, or phakic eyes, the temporal relationships between the use of latanoprost and developing CME, and the resolution of CME following cessation of the drug, suggest an association between latanoprost and CME. STOP2 localized in the nucleus and regulated transcription of two genes (PGIP1 and PGIP2) associated with cell wall stabilization at low pH.

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The source of the auto fluorescent light emission are amino acids of the collagen molecules. Surgical treatment of malignant carcinoid tumours of the appendix. Optical recordings of the same preparations stained with the voltage-sensitive dye RH414 were also made. Type (i) was related to basal membrane and up-regulated in differentiated 3T3-L1 cells and in histogenesis at depot-specific timings.

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Visual acuity, refractive and keratometric results of 140 consecutive radial keratotomy procedures. RESULTS of the present study for the first time provided the possibility of producing rSK from a local and native source with comparable yields and activities similar to the standard strain.

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The response to course TG results from cardioprotective action of constant electric current on ischemic myocardium which limits the zone of the lesion thus reducing early fatal cases number and preventing cardiogenic shock. The differentiation characteristics of HPC support the concept that pericytes are primitive cells that may act as precursors to other mesenchymal cells. Rejection-induced coronary obstruction should be considered in patients with repeated acute rejection episodes who are predisposed to the development of vascular rejection.

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The study of the protein fractions thus obtained in the immunodiffusion test with rabbit antiserum to the initial protein preparation revealed that these proteins contained type-specific components, 3-6 type-nonspecific protein antigens common with protein antigens of M 1 and M 12, as well as one protein antigen common with type M 1. Method SiteGA for the recognition of transcription factor binding sites The results implicate that Hippophae rhamnoides is an effective antioxidant, and one of the important mechanisms of Hippophae rhamnoides in anti-atherosclerosis reported recently may be closely related to the action of anti-lipid peroxidation. Percutaneous central venous catheterization in a pediatric intensive care unit: a survival analysis of complications. Using an analysis based upon Land Capability for Agriculture in Scotland, it is shown that this dynamism not only involves the long-term average but also shorter term spatiotemporal patterns, particularly through changes in interannual variability.

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A 58-year-old male with locally recurrent rectal cancer and liver metastases was referred to our hospital. The data obtained suggested that the recycling of EGF-receptor complexes is relatively independent of their degradation. A minute fragment was found in the metaphase plates obtained from one Holstein bull carrying Robertsonian translocation. In addition, these groupings of DoF corresponds to well-defined anatomo-functional finger joints according to muscle groups.

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Outcomes were compared between patients with L4-L5 involvement and patients with L5-S1 involvement. Meta-analysis of clinical studies of systemic effects of hormonal replacement therapy with the use of testosterone is conducted and problems of safety of its long term use are studied. Vitamin D deficiency has been implicated in susceptibility to the development of metabolic syndrome, obesity and type 2 diabetes mellitus. A cross-sectional study with control group was performed on fresh tissue samples from 25 patients with nasal polyps, and 25 persons with concha bollusa (control group). We applied the qualitative methodology of constant comparison to analyze the data, whereby two researchers independently analyzed the results into textual themes.

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The condition is still serious with a poor prognosis, and the therapeutic regimen is not yet standardized (cryosupernatant and factor VIII free plasma, steroids, immunoglobulins, anticoagulation, dextrane, prostacyclin, vincristine, splenectomy?). High mRNA levels were found in young developing organs such as cauline leaves while they were significantly lower in rosette leaves, stems and inflorescences, and almost undetectable in roots. Nebulized L-epinephrine has been recommended for the treatment of viral croup.

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New designs of ventricular catheters for hydrocephalus by 3-D computational fluid dynamics. Parental occupational paint exposure and risk of childhood leukemia in the offspring: findings from the Childhood Leukemia International Consortium.

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The finding that high-fat fed LDLR-/- animals with CKD had hyperphosphatemia which was prevented in BMP-7-treated animals lead us to examine the skeletons of these mice. Cannulation of the neurovascular sheath with a G22 spinal needle. Poorly differentiated carcinoma or adenocarcinoma of unknown primary site: long-term results with cisplatin-based chemotherapy. CT angiography clearly depicted the entire aorta, the supra-aortic vessels, and the ilio-femoral arteries in all patients.

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The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript. In this article current knowledge regarding plasmids resident in the human gut mobile metagenome is reviewed, and available strategies to access and characterize this portion of the gut microbiome are described. Histologic diagnosis by endoscopic ultrasonography guided fine needle aspiration (EUS-FNA) was glomus tumor. Serum urate levels and gout duration were identified as the principal determinants of tophi development. Concurrent with the rise in obesity, nonalcoholic fatty liver disease is recognized as the leading cause of serum aminotransferase elevations in obese youth.

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In 100 patients with cervicogenic vertebral basilar insufficiency of cerebral circulation was performed clinical and neurological examination, and transcranial Doppler arteries of vertebral basilar area. The tested compounds (2a, 2b, 2d) showed good activity comparable to that of carboplatin. Psychologic distress has an independent effect on medically certified sickness absence. A TaqMan based polymerase chain reaction (PCR) assay was developed for the detection and quantitation of varicella zoster virus (VZV).

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An overview of the role of federal surveyors and their work with state agencies and long-term care facilities. However, more cases, well characterised both for phenotypic signs and genomic details, are needed to further restrict candidate regions for phenotypic signs in 16q deletions. Furthermore, SCI patients mainly showed decreased inter-hemispheric FC between the bilateral primary sensorimotor cortex, as well as increased intra-hemispheric FC within the motor network, including the primary sensorimotor cortex, premotor cortex, supplementary motor area (SMA), thalamus and cerebellum. The contribution of nursing science to interprofessional knowledge development

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The results of this study suggest that NGC stimulation generates several components of nociception, including behavioral arousal, autonomic nervous system-mediated responses, aversive affect, and motor responses. The feasibility of this novel nanoshell soldering technique was studied by assessing the local heating of the area and tensile strength of the resulting fused tissue. New-association priming of word identification in normal and amnesic subjects. The MAP was recorded from a needle electrode that was inserted to the thoracic erector spinae muscle, quadriceps muscle and crural triceps muscle.

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Comparison of effects of oxygen and antioxidative enzymes on cell growth between retinal pigment epithelial cells and vascular endothelial cells in vitro. This contribution offers an example as to how implement risk management in early-stage biosimilar development as part of the QbD concept.

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A PCR-based search for splice variants of the VPAC2 G protein-coupled receptor for vasoactive intestinal peptide (VIP) revealed: (a) a short-deletion variant in mouse lymphocytes termed VPAC2de367-380, that lacks 14 amino acids in the seventh transmembrane domain, and (b) a long-deletion variant in human lymphocytes termed VPAC2de325-438(i325-334), that lacks 114 amino acids beginning with the carboxyl-terminal end of the third cytoplasmic loop and has 10 new carboxy-terminal amino acids. Numerous indexes have been derived for the assessment of ventricular function, suggesting that none is ideal. The diagnosis of recurrent cardiac hydatidosis was made by two-dimensional echocardiography and computed tomography and was confirmed by clinical and biochemical findings. These results demonstrate that SRF is targeted by several signal transduction pathways within cells and establishes SRF as a nuclear target for MAPKAP kinase 2. Lactate dehydrogenase (LDH) activity and the character of its isoenzyme distribution in pancreas of the human embryos and feti of the 5th-13th-week development were studied.

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The aim of the study was to assess whether the immunoreactive inhibin response to ovarian stimulation in polycystic ovarian syndrome was of predictive value for the outcome of ovulation induction. Flow through lattice networks with quenched disorder exhibits a strong correlation in the velocity field, even if the link transmissivities are uncorrelated. The effects of ionized and nonionized compression garments on sprint and endurance cycling. An immunohistochemical study of 28 cases with special attention to the role of myofibroblasts. Atrial fibrillation in patients with sick sinus syndrome: the association with PQ-interval and percentage of ventricular pacing.

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Effects of levosimendan on glomerular filtration rate, renal blood flow, and renal oxygenation after cardiac surgery with cardiopulmonary bypass: a randomized placebo-controlled study. Catheter placement failures, catheters failed to be placed in the first attempt, attempts per catheter inserted, time taken for successful venous puncture, and complications (carotid artery puncture, pneumo- or hemothorax, neck hematoma, and brachial plexus injury).