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Neuroendocrine carcinomas (NEC) of the prostate are rare, with only a few series hitherto reported. Ethnic differences in diabetes-related measures were estimated using analysis of variance/covariance. Exposed Root Interactions Symposium: consensus and recommendations.

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Toll-like receptors play an important role in the innate immune response to invading pathogens and recently have been demonstrated to be expressed on mice cornea. Information pertaining to signalment, imaging findings, clinical signs, duration of clinical signs, preoperative treatment, location of the tumor, results of histologic assessment, outcome, and necropsy results was obtained from the medical record.

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A comparison of the regulated genes to known regulons suggests the involvement of the global regulators CodY and SigB in shaping the response of S. It was found that GH treatment of RGCs reduced Akt levels, while concomitantly raising Akt-phos levels, consistent with a role for Akt signaling pathways in GH neuroprotective action. Sigmoid colon vaginoplasty is a special procedure which appears appropriate for the construction of a new vagina in children.

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Psoriasis is associated with higher prevalences of cardiovascular and metabolic comorbidities in adults but the relationship of age at onset and those prevalences is unknown. Human ApoA-I structure, as analyzed by electrophoresis and MS, was found severely altered by hydroxyl radicals in vitro. The smaller rounded spots were restricted to the lips of the hair infundibula. In Ethiopia, although labor abnormality and its complications like obstetric fistula are highly prevalent, there is no published study that determines the predictors of labor abnormalities.

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Basic calcium phosphate crystals induce NLRP3 inflammasome activation: the in vitro and in vivo face to face. Thoracic extraosseous, epidural, cavernous hemangioma: Case report and review of literature. Symptoms result from the direct effects of the virus on the immune system and the nervous system, which appear to be the primary targets. In a systematic review of the literature published between January, 1990 and December, 2011, we found 52 suitable studies, many providing prevalence estimates for several age groups.

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Growth inhibitory effects of flavonoids in human thyroid cancer cell lines. Neuropsychological changes following military service in Iraq: case proven, but what is the significance?

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Gingival hyperplasia is a rare condition and is of importance for cosmetic and mechanical reasons. In the present study, the standard free energy change was investigated for the formation of boron nitride with nitrogen partial pressures. Overall, different stages of cold response elicited changes mainly in genes involved in heat shock response, circadian rhythm and metabolism.

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Changes in Streptococcus pyogenes causing invasive disease in Portugal: evidence for superantigen gene loss and acquisition. Relevant demographic, clinical, anthropometric, and analytic information was obtained from all participants. The value of D in square centimeters per second x 10(5) at 30 degrees C is 1.34, 1.65, and 1.88 in the following zeolites, respectively: Na X, Ca X, and Ca Y (X and Y being an indication of ratio of silicon to aluminum in the zeolites).

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Genetic screening for C9orf72 hexanucleotide expansions was performed in 343 patients, and SOD1, TARDBP, and VCP were tested in the subgroup of patients with a family history of ALS. nov., a novel pathogen that affects Asian pear trees (Pyrus pyrifolia Nakai)

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The easy ECG system connected 4 therapeutic-and-prophylactic institutions of a rural area and the town of Uryupinsk with the Research Institute of Cardiology, Russian Cardiology Research-and-Production Complex (Moscow). Single-stage operation without colostomy was safe with good outcomes in patients with perineal fistula. All-trans retinoic acid (RA) has previously been shown to modulate the transcriptional properties of the retinoic acid receptor (RAR) and retinoid X receptor (RXR). The breath of life: legacies from virtuosos of biology, chemistry, and medicine.

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In addition, the recent discovery of small molecular agents with high potency and specificity for the endothelin A receptor subtype may also be of value in specific vascular disease states. This effect persisted for the first three hours but was no longer detectable in either lean or genetically obese animals at 6 hours. Serum samples from 901 allergic patients, stratified in 6 groups according to age, were analysed by ImmunoCAP ISAC, a microarray chip that allows to identify the presence of specific IgE towards 103 different allergen components.

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Our results may provide fundamental insights into the mechanism of contact hypersensitivity-induced hair cycle/growth. We therefore continue to use curare, a nonsteroidal drug with a long history of safety, for long-term paralysis in these patients. Staging laparoscopy with laparoscopic ultrasonography optimizes patient selection for liver resection with curative intent. Current guidelines in trigeminal neuralgia management recommend sodium channel blockers--carbamazepine or oxcarbazepine--as the first-line treatment.

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A second approach looked at hospital obstetric charts, and the third approach looked at admission and discharge data, as well as cost figures for NICU admissions from the target area. Inhibition resulted from competition between activation domains of effectors and competitors for a limiting cellular cofactor. Implementation of biopsychosocial treatment, though mandated by process-of-care guidelines, may be limited in the field of sexual health owing to resource limitations, limitations in physician training curricula, and structural obstacles preventing interdisciplinary collaboration. Surprisingly, combining these two positive manipulations induces growth cone collapse and retraction on laminin but not on fibronectin. Application of Spiroplasma melliferum proteogenomic profiling for the discovery of virulence factors and pathogenicity mechanisms in host-associated spiroplasmas.

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Inter-operator variability was assessed for PC-MR measurements and reproducibility was tested by repeated scans in one fetus. However, most of the information thus far available has been derived from experiments performed using Long Term Bone Marrow Cultures and there is as yet no information regarding the haematopoietic microenvironmental status of the developing liver. Negative control of BAK1 by protein phosphatase 2A during plant innate immunity. Time period of immobility and pressure ulcer development in spinal cord-injured patients.

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Using sets of two-dimensional diffusion-relaxation measurements in applied and internal gradients, we study in detail the correlation between the field inhomogeneities, restricted diffusion, and relaxation time in three rocks of different susceptibility. Subunit 8 of yeast mitochondrial ATP synthase is a small hydrophobic component of the membrane-associated F0 sector. Novel application of high pressure processing for the production of shellfish toxin matrix reference materials.

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This study demonstrated the viability of the prediction tool in determining drug release profile of electrospun core-shell nanofibrous scaffolds. Recent work illuminates how the motor-driven poleward sliding of MTs - nucleated at centrosomes, chromosomes and on pre-existing MTs - contributes to spindle assembly and length control. The authors studied prevalence of atherosclerosis, serum levels of lipids and homocysteine in coal miners suffering from pulmonary dust diseases.

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This is the first-in-human demonstration of identifying pulmonary nodules during thoracic surgery with NIR imaging without a priori knowledge of their location or existence. Implications of these findings are discussed, with special reference to education, peer counseling, and psychotherapy. Bio-inspired nano-materials can be formed by the ordered assembly of elementary building blocks using recognition modules and structural elements.

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The heavier liver and muscles in Suffolk fetuses may suggest increased amino acid transport across the Suffolk placenta in the absence of breed differences in gross placental efficiency. Intrathecal magnesium can prevent spinal cord injury despite markedly negative spinal cord perfusion pressure during thoracic aortic cross-clamping in a canine model of spinal cord ischemia.

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The total number of learning objectives, contained within 13 sub-classifications, was 221 (including 35 of supplementary clinical occupational health). This paper reports the first national level analysis of police and citizen justifiable homicides for a twelve year period. Our purpose in bringing this incident to light after so many years is to point out the relevance of the extensive studies of the problem which were conducted in the 1930s and 1940s to the current situation and to suggest that health care students are vulnerable to airborne infections as well as those spread by inoculation injuries.

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Evaluation of myocardial deformation, particularly of RS, appears to be a sensitive technique for detection of myocardial involvement in patients in the indeterminate form and provides insights into the still unrevealed pathophysiology of Chagas heart involvement. These cases support the hypothesis that acquired cystic disease of the kidney is not restricted to patients treated with maintenance dialysis. Gilthead seabream is a fish species of great importance in Mediterranean aquaculture, attracting many studies on nutrition and chronobiology, although nothing is known about the effect of feeding frequency on the daily rhythms of the gastric digestion process.

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In the case of sentinel hemorrhage, aortography is the initial diagnostic procedure of choice, followed by flexible esophagogastroscopy if necessary. Therefore, EGCG is capable of regulating immune-mediated liver injury in vivo. So far, only a few prospective studies have investigated the effect of adaptive salutogenic mechanisms on CRF. Clarification on the relationship between diet and enamel thickness among mangabeys is important not only because of recognition that mangabeys are not a natural group but also because of recent arguments that explain thick enamel as an evolved response to the seasonal consumption of hard foods.

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Molecular characterization of human stathmin expressed in Escherichia coli: site-directed mutagenesis of two phosphorylatable serines (Ser-25 and Ser-63). Impaction and pushout tests were performed with each of five ceramic inserts in titanium shells per test to simulate clinical intraoperative situations of misaligned inserts (Test 1), deformed shells (Test 2), soft tissue within the locking taper area (Test 3), simulated cup taper damage (Test 4), and a combination of misaligned insert, deformed shells, and simulated taper damage to create an overall worst-case condition (Test 5). The MIG full-length cDNA was amplified from pBLAST-MIG and was cloned into the eukaryote expression vector pORF-mcs, and the resulted recombinant plasmid was named pORF-MIG.

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fennelliae in a non-HIV-infected, heterosexual, immunocompromised patient. A method of evaluation of the operation-anesthesia risk in great and extremely great resections of the liver with special reference to specific features of the concrete operation is described. Falls-related self-efficacy was independently associated with both balance and mobility after accounting for age, current physical activity level, and performances in relevant physiological domains. Adenosine A1 receptor-mediated inhibition of myocardial norepinephrine release involves neither phospholipase C nor protein kinase C but does involve adenylyl cyclase.

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The new complexes, 5-iodoindazolium trans-tetrachloridobis(5-iodoindazole)ruthen(III)ate (1) and 5-iodoindazolium trans-tetrachlorido(dimethyl sulfoxide)(5-iodoindazole)ruthen(III)ate (3), were characterized by elemental analysis, mass spectrometry and UV-vis spectrophotometry. Relief from painful diabetic neuropathy is an important clinical issue. atozf2 antisense lines were more sensitive to ABA and salt stress during the seed germination and cotyledon greening processes. Transgenic PKC betaII mice exhibit hyperproliferation of the colonic epithelium and an increased susceptibility to azoxymethane-induced aberrant crypt foci, preneoplastic lesions in the colon. To find out whether there is any correlation between class attendance and academic performance.

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Stage of change for making an informed decision about Medicare health plans. It is easy to cause distant metastasis and has a poor prognosis. By Giemsa C-banded karyotype, the chromosome constitution of amphidiploid plants was found to result from exact doubling of the chromosome sets of amphihaploid common species.

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Gaucher disease: four rare alleles encoding F213I, P289L, T323I, and R463C in type 1 variants. Nebulized heparin may reduce fibrin cast formation and reduce the degree of airway obstruction in burn inhalation injury. In CT scan, Hounsfield Unit (HU) is proportional to the degree of x-ray attenuation by the tissue.

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A marked Q wave in these leads is not necessarily a manifestation of clinical disease (it may be due to a changed position of the electric axis of the heart) and conversely the absence of the Q wave in leads II, III, aVF does not imply clinical absence of disease (most frequently a low myocardial infarction). Cystoscopy is a common ambulatory procedure performed in Urology and can be associated with moderate pain and anxiety. Dark myelin sheaths, standing out against a pale background, were identified by a binary transformation of the computer-stored image. Recently, aspects of this model have been tested using powerful genetic strategies in both Arabidopsis and Physcomitrella.

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Recent experiments show how stimulation of neurons in the frontal eye fields can mimic this process. Here we address this problem by taking a detailed look at simple past tense verbs in the Corpus of Historical American English. Staged development of dysbiotic disturbance of the upper airways was revealed in children suffering from stenosing laryngotracheitis in the presence of viral infection.

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SNA has a favorable prognosis with treatment, whereas the prognosis for SOA remains poor. A prospective randomized, double-blind phase I/II intrapatient comparison study was conducted in 12 patients to investigate whether topical ALA PDT is an effective treatment for chronic plaque-type psoriasis. These data suggest that MYCN stimulates the expression of not only MCM7, which is a well defined MYCN target gene, but also of the complete minichromosome maintenance complex. The clinical results of both single-row repair and dual-row repair are satisfactory. This paper presents these sleep education programs and evaluates their effectiveness.

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One of them was a new natural product, namely propinqualin, whose structure was established as (-)-epiafzelechin-3-O-beta-D-allopyranoside. We evaluate the local properties of the graphs by measuring the meshedness coefficient and counting short cycles (of three, four, and five edges), and the global properties by measuring global efficiency and cost. In order to evaluate the potential utility of the validity measures for the Basic Personality Inventory (BPI) the relationships between validity measures and content scales were evaluated in a sample of 71 inmates. Lack of effectiveness of combined 5-fluorouracil and leucovorin in patients with 5-fluorouracil-resistant advanced colorectal cancer.

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Insufficient cooking, faulty food storage, and improper reuse of leftovers have all been neglected topics. Professionalism in medicine requires preparation for the globalized world. The analysis of detection rate of eggs of opistorchis in copromaterial and level of anti-opistorchis antibodies in samples of blood serum of patients demonstrated the presence of strong direct correlation relationship between these indicators.

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Serum levels of steroid hormones in men with varicocele and oligospermia as compared to normozoospermic men. We modified a biosafety level 2 chimeric virus system to facilitate evaluation of inhibitors directed against highly pathogenic coronaviruses. Concurrent naltrexone and prolonged exposure therapy for patients with comorbid alcohol dependence and PTSD: a randomized clinical trial. Women with a high Zung depression score, high active coping, high avoidance, and a high expression of emotion have lower pregnancy rates.

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Comparisons of fatty acids between the 3 groups did not reveal significant differences. Validating and Improving Injury Burden Estimates Study: the Injury-VIBES study protocol.

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The in-line rainbow trapping is important for potential applications including optical storage, slow light, optical switch and enhanced light-matter interactions in fiber integrated devices and highly integrated optical circuits. Effect of culture in vitro and organ culture on the dry mass of preimplantation mouse embryos. Deletion of the RAS genes in such a tpkw1 bcy1 strain had no effect.

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The histopathologic diagnosis was diffuse large B-cell lymphoma. The affected couples had at least one child from the current union in 23 of the 47 cases of reproductive disability. Altered microvascular response to adenosine in the spontaneously hypertensive rat. We tested fimbriae production, adhesion to uroepithelial cells, hydrophobicity, motility and hemolysin production of E.

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The virulent strain showed increased expression of heat shock proteins (HSPs) of 110, 83, 70, 65, 40 and 12 kDa on heat shock (37 degrees C), while the attenuated form showed increased expression of HSPs 83, 70 and 65 only. The activation of cAMP-dependent protein kinase is directly linked to the stimulation of bone resorption by parathyroid hormone. We hereby report a novel GBA2 mutation associated with spastic ataxia and suggest that GBA2 mutations may be a relatively frequent cause of ARCA. Although not a traditional aspect of their responsibilities, information from this review can help school nurses implement a school-based CSA prevention program.

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Overall, the data suggest that HMGB1 may be an important regulator of UV-induced cutaneous inflammation and tumor formation. 1994), whose interaction with the carboxy-terminal repeat domain of RNA polymerase II enables transcriptional activation. After castration, mRNA expression levels of specific growth factors, such as Fgf2, Fgf7, Hgf, Tgfa, and Tgfb, were relatively abundant in whole mouse DLPs. langeroni had fed on human blood, 2 on dog, 1 on cat, and 1 on rat blood. To elucidate whether the microvascular volume (MV) of the Achilles tendon is elevated in patients with AT compared with healthy controls during pre-exercise rest, after acute exercise, and 24 hours after exercise.

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Unsaturated fatty acids are essential lipid components of Mucor rouxii. The first reports describing the cloning and characterization of PELP1 showed that it was an estrogen receptor coactivator. Spaceflight appears to initiate cellular remodeling throughout the plant, yet specific strategies of the response are distinct among specific organs of the plant.

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The knowledge base is made up of three components: an expressive ontology formalized in the Web Ontology Language (OWL 2 DL), a Resource Description Framework (RDF) model for capturing detailed results of manual annotation of pharmacogenomic information in drug product labels, and an RDF conversion of relevant biomedical datasets. The aim of this study was to use an in vitro colonic simulator to determine the rates of metabolism of these three prodrugs in the presence of colonic bacteria, and to link the data to results obtained previously in humans. Results were applied spatially to evaluate eight Bay-wide climate change scenarios. Increased lead absorption in children living in an area with high concentration of ceramic workshops. Clinical resolution and CSF viral suppression were observed after switching to a genotype-guided combined antiretroviral regimen with good CSF penetration.