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We evaluated the anatomic location of the external anal sphincter (EAS) to pelvic bony landmarks related to 3-dimensional conformal radiotherapy (3DRT) and studied the dosimetric coverage of the EAS in patients undergoing neoadjuvant chemoradiation for rectal cancer. This was followed by a search for papers published since these systematic reviews on Medline and supplemented by limited iterative searching from reference lists. The proliferation of cultured HeLa cells were significantly inhibited by Jumi extract in a dose-dependent manner. In this study, the previously developed R program language-SWAT-Flexible Modeling Environment (R-SWAT-FME) was improved to support multiple model variables and objectives at multiple time steps (i.e., daily, monthly, and annually). The influence of age and gender on lumbar spine sagittal plane range of motion.

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Reduced apoptosis by combining normobaric oxygenation with ethanol in transient ischemic stroke. A test to determine the epitope specificity of monoclonal antibodies (MCA) was developed for hybridoma clones producing antibodies against Newcastle disease virus (NDV). In the case of prelamin A, there is an additional farnesylation-dependent endoproteolysis, which is defective in two congenital diseases: Hutchinson-Gilford progeria (HGPS) and restrictive dermopathy (RD). It showed that biodegradation rate of aniline was increased with the augment of protein concentration in cell-free extract of Delftia sp.

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Immunopharmacologic study in mice of 2 beta-1, 3, beta-1, 6 polysaccharides (scleroglucan and PSAT) on the activation of macrophages and T lymphocytes The endoscope is a rigid virtual robotic endoscope that provides complete visual coverage of a three-dimensional space by controlling an adjustable viewing direction with three degrees of freedom.

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For the first time, we experimentally revealed spatial separation of focused light in different spots, which could be the basis of a micro-bio-spectrometer. To study the role of visual perception of phonemes in visual perception of sentences and words among normal-hearing individuals.

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In 38 cases therapy was changed in the frame of a one-week, small-group, inpatient, structured educational course. Patients with coronary artery disease undergoing mitral surgery were randomly allocated to receive either sevoflurane (50 patients) or propofol (50 patients) as main hypnotic. Overall counts were so low that data had to be converted to results100mL(-1). The causal association of HPV with cervical cancer, and increasingly with rising numbers of squamous cell carcinomas at other sites in both men and women, is increasingly recognised, while the morbidity of cutaneous HPV lesions, particularly in the immunosuppressed population is also significant.

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This chapter provides an overview of fluorescent labelling of different reactants related to the biochemistry of motor proteins. On sagittal sections, the fat has a variable appearance, but a constant location along the spinal canal. The advantages of this treatment modality for patients with familial chemodactoma are discussed.

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This paper is focused on the types of sleep problems that are associated with ADHD symptomatology, and attempts to untangle confounding factors and overlapping symptoms. Immobilization on epoxy supports is carried out as a two-step mechanism: in the first step the adsorption of the protein is promoted and in the second step the intramolecular covalent linkage among epoxy groups and nucleophiles of the protein is produced. Subsets of ATP-sensitive potassium channel (KATP) inhibitors increase gap junctional intercellular communication in metastatic cancer cell lines independent of SUR expression. Moreover, we also noted that SlNAC4 could not be induced by ethylene and may function upstream of the ripening regulator RIN and positively regulate its expression.

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A Macintosh II computer coordinates the movements of the robotic arm, the switching of over 40 solenoid valves and the monitoring of sensors in the workstation. Our study revealed that the prevalence of hypertension was higher in migraineurs without aura in comparison with non-migraineurs.

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Exploring alternative narratives: the prioritisation of polio in northern Nigeria. Strong, specific predictors can lead to patient-tailored treatment. Neither parent-offspring regression nor an animal model revealed significant heritability in clutch or egg size.

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Commonly cited facilitators were physician training, increased office staffing, and greater mental health, social services, and addictions support. The most important prognostic factors are the completeness of resection and the pathologic nodal status. Revealing the experience of mothers when massaging their children to know the phenomenon in the context of a mother-child healthy development. In 614 patients with pains in the right hypochondrium the cyto-bacterioscopy and bile culture were performed. Prostatic lesions developed in these mice in a predictable and heritable manner, indicating that Neo did not alter Tag-induced prostate tumor development and progression.

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The F proteins of the three SSPE strains were functional and co-expression with H protein from the MV wild-type or SSPE strains in this study induced formation of large syncytia in Vero cells as well as in cell lines expressing SLAM or CD46. We identified PDGFA as a SOX11 direct target gene upregulated in MCL cells whose inhibition impaired SOX11-enhanced in vitro angiogenic effects on endothelial cells. Development of a standardized anticoagulation protocol for the Impella device that factors the heparin-based purge into the total heparin dosage and makes appropriate adjustments based on the fluctuating rate of the purge solution can provide effective anticoagulation to patients receiving extended circulatory support from this device. The genome survey was conducted at 10-cM resolution for simple sequence tandem repeat polymorphisms (SSTRPs) that identify genes for Successful AGing (SAG loci) by virtue of linkage disequilibrium. The aim of this study was to compare the outcomes of unplanned and planned PV resections as part of PD.

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The aim was to shift their luminescence maximum towards optical communication wavelengths at 1.3 or 1.55 microm. Not only is it the rate-limiting step in the steam reforming of natural gas, the reaction exhibits interesting mode-selective behavior and a strong dependence on the temperature of the metal. Differences between genetic and physical centromere distances in the case of two genes for male sterility in barley. Results also showed involvement of classical mTOR pathway in autophagy induction by iron oxide NPs in A549 cells. Additional articles were identified through a manual search of reference lists of the articles obtained.

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Lateral orbit approach operation involved many important structures in the orbit. Comparison of antigenic sites of the envelope glycoprotein of the Iranian isolate of human T-cell leukemia virus type 1 with different subtypes of the virus. Prognostic parameters (exercise induced changes in effective orifice area, ejection fraction, and global longitudinal strain) may help risk-stratify patients with moderate or severe mitral regurgitation who are asymptomatic.

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It further has to be investigated whether this concept of a regulatory dysfunction, as observed in lymphocytes from schizophrenic patients, can be applied to the CNS in general. Discussion Comparisons were made and ratios established between physican estimates of patient radiation exposure from nuclear medicine procedures and estimates of CT procedures. These data, together with known physicochemical properties of Casodex suggest that a blood-brain barrier exists for the drug which results in exclusion of this antiandrogen from central sites of androgen negative feedback and that this accounts for its peripherally selective antihormonal profile. Endpoints of the study were local control (LC), locoregional control (LRC), disease-free survival (DFS), overall survival (OS), late toxicity, quality of life, and voice handicap index. Irregular border of the thyroid mass, extension of tumor mass into mediastinal fat or chest wall, or lymphadenopathy suggested the malignant nature of the primary tumor.

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With aging, activation of the B cells progresses and they appear to down-regulate the IL-2 hyperresponse of B cells and the IL-2 synthesis by T cells. All possible forms of inferior alveolar nerve injury are examined with a report on several personal cases and their medicolegal implications. Approbation of the method on dogs has demonstrated its atraumaticity and safety. Endothelin-1 contributes to endothelial dysfunction and enhanced vasoconstriction through augmented superoxide production in penile arteries from insulin-resistant obese rats: role of ET(A) and ET(B) receptors.

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This study evaluated whether the interaction of SDF-1 with CXCR4 could block constitutive apoptosis of peripheral blood neutrophils from congenital neutropenia patients and controls. The fungal fast lane: common mycorrhizal networks extend bioactive zones of allelochemicals in soils. In one case insulin tolerance test revealed an adequate decrease of blood glucose before and after ACTH-Z therapy, and there was a poor GH response after ACTH-Z therapy. NO concentrations were more than 100 times higher in the patients than in the controls.

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Recent studies showed that para-aminosalicylic acid is recognized as a substrate by dihydropteroate synthase and poisons the downstream folate pathway. Four subjects participated in the partial report task, and their performances were compared by using two types of stimuli: mixed-character matrix (alphabet, katakana, and kanji) and single-character matrix (one of the three characters), under the tachistoscopic presentation.

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Only clinical trials evaluating cardiovascular end points of statins used in patients with ESRD were included. They could identify those patients who would benefit from administration of Kampo medicine only by administering the treatment. The inputs from different intersegmental interneurons could then modulate these pathways independently.

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Continuous peroral administration of antifungal drugs was not successful, and he expired with severe dyspnea. Application to existing drug molecules: mifepristone 1 and antalarmin 8. A novel and highly efficient photocatalyst based on P25-graphdiyne nanocomposite. During the course of immunodeficiency diseases, severe candidiasis can occur with extensive cutaneous and mucous membrane lesions.

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Instead, different hormones appear to regulate distinct members of protein families. Its recent development owes much to the advent of digital technologies which make it easier and more accurate to interpret the changes observed in left ventricular regional kinetics by comparing the data at rest with those recorded at peak physical effort. Maternal serum homocysteine level is increased in 11 to 14 weeks of gestation that is complicated with pre-eclampsia, gestational hypertension, intrauterine growth restriction and preterm birth.

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However, microscopic observation of myelin in living organisms remains a challenge. Direct IR observation of vibrational properties of carbonyl species formed on Pd nano-particles supported on amorphous carbon: comparison with Pd/SiO2-Al2O3.

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The observation showed that the suppressive activity in the sera of preoperative ovarian cancer patients was higher than that in the sera of gastric cancer or lung cancer patients. As splenic perfusion values fell, the size of the regions that showed late enhancement increased. Orthopedic trauma surgeons and care teams can expect similar acute care outcomes in morbidly obese and non-morbidly obese patients with acetabular fracture. Overall, these results highlight the advantages of applying modern methods in natural products-based research to accelerate the HT discovery of therapeutic leads and/or new molecular structures using LC-MS-UV-ELSD-based libraries.

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Acetabular roof reconstruction with pedicled iliac graft: ten years later. 3D constitutive modeling of the biaxial mechanical response of intact and layer-dissected human carotid arteries. Four patients had vague symptoms of myalgias and fatigue without classic findings, and five had concomitant nutritional deficiencies. This study evaluates the physiologic mechanism by which inhaled NO improves pulmonary function in an ovine model.

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Ultrasonography can show the inflammation changes of the knee joint and can be a usefull method in diagnosis of Lyme arthritis. This provides a good argument for the accuracy of the immunoenzymatic method.

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This study addresses some of the difficulties inherent in studying the effect of pregnancy on disability resulting from MS. To investigate whether exposure to toxic gas mixtures change the effect of a single gas exposure on immune function, BALB/c mice were continuously exposed to 4.0 ppm nitrogen dioxide (NO2), 0.8 ppm ozone (O3), or the mixture of NO2 plus O3 for 3, 7, 14, and 56 days. Analysis of a larger group of patients is required in order to determine whether reactive thrombocytosis may contribute to the pathogenesis of stroke in some patients following cardiopulmonary bypass surgery. We measured the serum levels of lignocaine in 30 patients after the transurethral administration of 400 mg lignocaine gel just before transurethral prostatectomy. Numerous solutions mainly essential oils have been evaluated in the past as clearing agents, which can possibly be substituted for xylene during the routine tissue processing.

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Triple-combination treatments were well tolerated in all clinical trials reviewed. It is currently recommended in centres with appropriate expertise for the screening of patients with suspected congenital coronary anomalies.

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Assessment of site conditions for disposal of low- and intermediate-level radioactive wastes: a case study in southern China. AIRE protein is mainly expressed in thymic medullary epithelial cells, thus implying a strict control over its expression pattern. Angioplasty of the left main coronary artery--report of a case with left main coronary stenosis and aortic valve stenosis Indeed, data in the second year showed more rapid deterioration of function in some of the operated boys. Evaluation of two new immunochromatographic assays (Rapid U Legionella antigen test and SD Bioline Legionella antigen test) for detection of Legionella pneumophila serogroup 1 antigen in urine.

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Foam cushions and vacuum immobilizers were used to limit intra-scan motion artifacts. Cell survival of neurons and astrocytes was determined with dual-label immunocytochemistry. Moreover, one or two lymphocyte subsets had to be obtained from an identical PBL donor. In this case study a specially designed electrically powered mobile stand up device, for a patient with a complete spinal cord lesion under cervical level C7, is described. Simulating the effects of fluctuating dissolved oxygen on growth, reproduction, and survival of fish and shrimp.

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Allogeneic (7 cases) and autologous (2 cases) AS-derived cultivated corneal epithelial equivalents were transplanted onto the ocular surface. A Bruker EPR 300E and Andor 500i optical spectrograph incorporated with a Newton EMCCD camera are used for ESR and optical registration, respectively.

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The cost of sample transport from the clinic to the laboratory was estimated using spatial models. In this study, we probed EZH2 function in pancreatic cancer using diflourinated-curcumin (CDF), a novel analogue of the turmeric spice component curcumin that has antioxidant properties. VIP1 receptor mRNA is predominantly found in the lung, small intestine, thymus, and within the brain in the cerebral cortex and hippocampus. Thus the frequent monitoring of relative risk of human VL in small-areas is important to direct and prioritize the actions of the control program in urban environment, especially in big cities. The isoxal derivative, leflunomide (LF), is a new potent immunosuppressive which has been shown to be effective in preventing autoimmune disorders and reactions leading to organ transplantation rejection.

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During this period, a multidisciplinary BCS was initiated with emphasis on limiting intraoperative hemodilution, tolerance of perioperative anemia, and blood management education for the cardiac surgery care providers. This approach identified the membrane-associated peroxidase GPx8 as a bona fide cellular substrate of the HCV NS3-4A protease. DCS augmentation was evident only among individuals low in conscientiousness and high in agreeableness. Parenteral injection of buprenorphine can cause a wide range of vascular complications from simple vascular irritation to severe infective thrombosis and pseudoaneurysms requiring limb amputations. Characterization of the aldehyde reactive probe reaction with AP-sites in DNA: influence of AP-lyase on adduct stability.

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Because the application of MIS was limited to suspected EGC, the control groups were similarly limited to patients deemed to have EGC as shown by preoperative endoscopy, endoscopic ultrasound, or both. Only four percent of transplant candidates are transplanted for AIH but the risk for graft loss because of recurrence has to be considered and recurrent AIH treated after transplantation.

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Type 2 Diabetes results from a complex physiologic process that includes the pancreatic beta cells, peripheral glucose uptake in muscle, the secretion of multiple cytokines and hormone-like molecules from adipocytes, hepatic glucose production, and likely the central nervous system. Most pediatric patients with EDH can be managed with observation. Such identifications reveal much about the dynamics of calling to the helping professions and caring within them, and may serve a parabolic function, revealing aspects of God and community otherwise hidden. The purpose of this study was to determine whether electronic fetal monitoring can identify fetuses with metabolic acidosis and hypoxic-ischemic encephalopathy.

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Erythrocyte total GST and isoenzymes activities from 35 control subjects and 125 subjects of various anemias, including aplastic, hemolytic, iron deficiency and thalassemia anemias were measured spectrophotometrically. To present the experience of laparoscopic sleeve gastrectomy in adolescents with morbid obesity, treated by the pediatric multi-disciplinary obesity clinic. Among 1150 retrieved articles, 71 articles were relevant over 20 years. We here describe the use of the FOX (ferrous oxidation in Xylenol orange) assay as a screen for detergent peroxide accumulation. Thus, glutamate antagonists may be a new therapeutic strategy for different inner ear diseases.

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We systematically analyzed the level of CP in Ts65Dn mouse, including serum CP concentration and enzymatic activity, CP mRNA in brain, the expression of CP protein in brain. Unlike the well-studied image-forming function in retinal photoreceptors, direct evidence characterizing the mechanism of chromatophore photoresponses is less understood, particularly at the molecular and cellular levels.