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Simple and highly efficient microvalve systems based on an ionic polymer-metal composite (IPMC) diaphragm actuator have been developed. This study tested the hypothesis that obesity-related cardiomyopathy is caused by impaired cardiac energetics. According to review of the problem heavy metals are one of the most hazardous constituents of xenobiotics.

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Antimicrobial-related severe adverse events during treatment of bone and joint infection due to methicillin-susceptible Staphylococcus aureus. QT dispersion increases in patients with systemic lupus erythematosus. The methods employed by the Environmental Protection Agency for providing soil data that was scientifically valid and of defensible quality for each of these monitoring programs are presented. Adiponectin is known to confer its cardioprotective effects in obesity and type 2 diabetes, mainly by regulating glucose and fatty acid metabolism in cardiomyocytes. Although tolerability was acceptable in RCC patients with previously untreated BM, sunitinib has limited efficacy in this setting.

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By mining the tumor tissue and cancer cell line encyclopedia genomic databases, we identified the first somatic mutations in the DP-1 gene and describe 53 distinct mutation events here. We measured glomerular responses to 30 different odors in the AL of honeybees using calcium-sensitive dyes. However, for many patients with terminal illness, strong opioids are necessary for efficient and effective analgesia. The Est-5 genes in alien species provide evidence for chromosome homoeology with wheat.

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Opening of the NMDA receptor ion channel pore is initiated by agonist-induced conformational changes in the extracellular ligand-binding domain (LBD) but the dynamic mechanism of this process remains unresolved. Understanding the pathophysiological regulatory role of microRNAs in acute liver failure.

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In this paper, we propose a data stream management system embedded to a smart card for handling and storing user specific summaries of streaming data coming from medical sensor measurements and/or other medical measurements. The analysis showed, that early complications after this procedure are very rare.

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Compared with other bone regenerative methods for implant placement, a superior quality of bone was found and a shorter healing period is required. Newer antiviral agents that will be used alone or in combination are under development. In these cases, resolution of CME was documented clinically after discontinuing latanoprost.

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Assessment and treatment of adenotonsillar hypertrophy in children. Fucosylated alpha-fetoprotein (AFP) is a highly specific tumor marker for hepatocellular carcinoma (HCC).

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In contrast to a growing knowledge based on adults, little is known about its prevalence, correlated factors, and associations with subjective sleep perception and daytime sleepiness in children. This paper addresses the Technology Assessment process as a sequence of the above steps. Each sample was exposed to doses of UV light (10 to 60 mJ/cm2 at 254 nm) and free chlorine (27 to 150 mg-min/L at 4 degrees C). Cardiac-specific deletion of Yap impedes neonatal heart regeneration, resulting in a default fibrotic response.

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Of the pharmacologic therapies utilized in patients with symptomatic disease, only angiotensin converting enzyme (ACE) inhibitors (and to a lesser extent, angiotensin receptor blockers, or ARBs) have been shown to improve clinical outcomes among patients with ALVD. The health and economic impact of such vaccines in the Canadian population are uncertain.

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The current findings suggest a relationship of the genetic determinants and activity of paraoxonase 1 to CV risk in RA patients, as assessed by the presence or absence of carotid plaque. The annexin-membrane binding causes small changes of annexin trimer structures, while has significant effects on lipid bilayer structures.

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Limit to detection for pure culture was 55 colony forming units (CFU). Retrograde leptomeningeal venous drainage was documented in every patient, classifying the lesions as Cognard Type IV.

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DNA methylation changes are potential pathways of environmentally induced health effects. Summaries were evaluated on several dimensions, including time to summary completion, summary length, and summary quality, which was measured on a 13-item scoring tool.

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Immuno-fluorescent staining of the debrided tissues using a specific antibody against staphylococci demonstrated the presence of thick clumps of staphylococci colonizing the wound bed. In recent years, prevalence of hypertension in China is growing rapidly. There are a lot of factors influencing the therapeutic effect of acupuncture and moxibustion for slimming, and only both the physician and the patient cooperate each other and pay attention to the factors, can the therapeutic effect be better increased. Both pyridyl-containing nanotubes (DWCNTs and SWCNTs) form a complex with zinc porphyrin (ZnP), as evidenced by the presence of two isosbestic points in the absorption spectra of the porphyrin upon addition of the pyridyl-functionalized nanotubes. Work of 15 teachers was observed and 20 other teachers were interviewed.

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Biological control of mosquitoes in scrap tires in Brownsville, Texas, USA and Matamoros, Tamaulipas, Mexico. Unfortunately, in this case, a radical cure was not provided, but we considered that urinary re-diversion using an afferent limb as ileal conduit can be a useful option for urethral recurrence after ileal neobladder reconstruction. In general, larger head diameters revealed an increase in ROM and higher resisting moments.

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The results of treatment of 37 patients, suffering diabetes mellitus, were analyzed, in 16 of whom--for critical ischemia of the lower extremities (LE) and purulent-necrotic form of a diabetic foot syndrome 2 courses of treatment using urokinase were done together with pathogenetic and symptomatic therapy. Concurrently, subsuperficial cisterns form under the plasmalemma of nerve cells. Prospective data are needed to investigate if the association between CVD and the MTP-493T/T genotype might be due to the increased sub-clinical proinflammatory state associated with this mutation. Systemic mastocytosis with an associated clonal hematologic non-mast cell lineage disease (SM-AHNMD) in an infant patient. Histopathology of the joints was also more severe in C1qtnf3(-/-) mice.

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Septal localization of penicillin-binding protein 1 in Bacillus subtilis. With the use of carcinoembryonic antigen (CEA) as a model which bonded to its specific aptamer and destroyed the sandwichlike structure, the energy transfer efficiency was lowered, leading to PEC response augment. We are reporting a case in which a 45 yr old male presented to accident and emergency department of our institute with complaints of pain abdomen, greenish vomiting, abdominal distension, fever and non passage of flatus and stool following alcoholic binge 15 days back. Altered creatine dependence of muscle mitochondrial respiration in vitro: what are the likely effects in vivo?

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Expression of group B protective surface protein (BPS) by invasive and colonizing isolates of group B streptococci. These mutations all exhibit a high degree of association with specific restriction fragment-length polymorphism haplotypes at the PAH locus. In particular, the linearity (sublinearity) of graphene conductivity at lower (higher) gate voltage is naturally explained as arising solely from impurity correlation effects in the Coulomb disorder.

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There was a lack of consistency in data collection throughout the publicly-funded homebirth programs due to different databases, definitions and the use of different guidelines. Measurements of current speed and direction from the sea surface to below 400 meters made on the equator in the eastern Pacific in April 1968 indicate that the Equatorial Undercurrent extends from 300 meters to the sea surface. The biochemical targets of maternal thyroid hormone (TH) action in fetal brain remain poorly defined. elegans, GLD-1 became essential for promoting XX spermatogenesis via changes in the tra-2 mRNA and evolution of the species-specific protein FOG-2. As a means of pursuing these types of investigations, the protocols described in this unit provide a reliable method for isolating lung microvascular ECs from mouse neonatal pups that can be serially passaged.

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Neonatal vitamin a supplementation: sex-differential effects on mortality? The chemokine CXCL12 has been implicated in protection and therapeutic regeneration after MI through recruiting angiogenic outgrowth cells, improving neovascularization and cardiac function, but the endogenous role of its receptor CXCR4 is unknown. Patients with end-stage renal disease (ESRD) and latently infected with Mycobacterium tuberculosis (LTBI) are at higher risk to develop tuberculosis (TB) than healthy subjects. The search for the breast cancer cure: shall we start all over again? Fibroblast growth factor and transforming growth factor beta repress transcription of the myogenic regulatory gene MyoD1.

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We show that for an open quantum system interacting with a nonequilibrium environment, where temperature is no longer a valid notion, a fluctuation-dissipation inequality exists. The same interactions are observed in tissue culture cells where we observe a synergy in between Axin and Notch in the regulation of Armadillo/beta-catenin. Our interesting results on the antiproliferative (in vitro) and antitumour (in vivo) activities of (1E,3E)-1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene (1-Naph-DNB) have more recently induced us to design and synthesize some new 1,4-diaryl-2,3-dinitro-1,3-butadienes characterized by a common arylnitrobutadiene array but with different geometric and/or functional properties. This complementation between the two molecules is clearly directional and is determined by the specific chemical contacts including mainly hydrogen bonds. We examined the early changes after lipopolysaccharide (LPS) injection in chronically alcohol-fed rats with or without splenectomy.

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In this population, women who currently smoke are weaker and have poorer balance and poorer performance on measures of integrated physical function than nonsmokers. We gave general anesthesia for the lower right lobe resection in an infant with congenital cystic adenomatoid malformation (CCAM).

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Monoclonal anti-Ig antibodies with specificity for mu, delta, or kappa chains, regardless of mitogenicity, induced increased c-fos and c-myc mRNA expression with kinetics and magnitude similar to that observed following stimulation of B cells with IL-4. Reorganizing a resuscitation room using Six Sigma (6S) principles. Thrombin-stimulated clot formation was completely inhibited by heparin. Plaques were visualized using a T(2)-weighted rapid acquisition with relaxation enhancement (RARE) sequence. Comparison with existing method(s): The major impetus for developing and refining the methods was the need to accurately quantify microglial activation states without reliance on manual morphometric counting of serial immunohistochemistry slides.

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We found that each component part of fetus brain developed heterochronously from the view point of volumetric analyses. A multicenter analysis which included 252 patients who sustained a femoral neck fracture treated with an arthroplasty.

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Insofar as prion-infected Prnp hemizygous mice exhibited accumulation of PrP(Sc) and down-regulation of Sho hundreds of days prior to onset of neurologic symptoms, Sho depletion can be excluded as an important trigger for clinical disease or as a simple consequence of neuronal damage. These new results, with an improved precision of about ten orders of magnitude, are discussed in the context of highly accurate results from quantum electrodynamics, atomic spectroscopy, and the standards of metrology. A compact automated analyser which could analyse constituents in biological fluids with a small sample volume and in a short time has been developed.

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Native youth and smokeless tobacco: prevalence rates, gender differences, and descriptive characteristics. The Effects of Total Flavonoids from Buckwheat Flowers and Leaves on Renal Damage and PTP1B Expression in Type 2 Diabetic Rats. The work deals with the results of experimental (200 animals) and clinical (20 patients) study into the role of the efferent link of the autonomic nervous system in regulating motor activity of the small intestine and the possibility of using direct electroenteromyography in the diagnosis of the stages of paresis and the degree of motor disorders in peritonitis. In this study we analyze the ISI sequence --the spike train-- generated by a simple network of neurons whose output activity is modeled by a jump-diffusion process. Recently TTV was discovered as a potential causative agent of non-A-E hepatitis.

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The use of RNase H and poly(A) junction oligonucleotides in the analysis of in vitro polyadenylation reaction products. Urinary bladder pheochromocytoma, an extremely rare tumor in children: case report and review of the literature. Masseter muscle tension, chewing ability, and selected parameters of physical fitness in elderly care home residents in Lodz, Poland. In the presence of cycloheximide, which blocks the steroidogenic effects of both hormones, proto-oncogene mRNAs were superinduced by both hormones.

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Perturbations to the 1H resonances in the NMR spectrum of antithrombin upon binding of the two series of heparin fragments are compared to those generated by intact heparin binding, as well as to the effects of binding of a synthetic high-affinity pentasaccharide. Mitral valve disease treatment in children must be conservative, in an attempt to solve the problem with the different available plastic technics and leave the valve substitution to be a last option. Identification of malignant cells in serous effusions using a panel of monoclonal antibodies Ber-EP4, MCA-b-12 and EMA. To quantify antielastase capacity, total immunoreactive alpha 1-antitrypsins and active alpha 1-antitrypsins were measured in alveolar lavage fluids. Further investigations demonstrated homozygous Factor V Leiden mutation and activated factor C resistance and Dengue IgM positivity in our patient.

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This rare case indicates that careful observation should be carried out during low-dose Ara-C therapy in view of allergic reactions. This article demonstrates the description and use of a new appliance for Class II correction. Human endogenous retroviral syncytin exerts inhibitory effect on invasive phenotype of B16F10 melanoma cells. This paper aims to explore the experience of Malaysian women presenting with advanced breast cancer with regards to their interpretation of breast symptoms.

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Under certain regularity conditions, we show that the LAND estimator is able to identify the underlying true model structure correctly and at the same time estimate the multivariate regression function consistently. Women performed at a higher level than men on episodic recall, face and verbal recognition, and semantic fluency, whereas men performed better than women on a task-assessing, visuospatial ability.

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Furthermore, we demonstrate that these MBP-primed Th2 cells entered into the central nervous system and increased the expression of neurotrophins in vivo in the brain. The goal of this study was to evaluate the association between patient quality of life (QoL) and survival in pancreatic cancer patients undergoing care in a community hospital comprehensive cancer center. Unmetabolized butyrate enters the nucleus and functions as a histone deacetylase (HDAC) inhibitor that epigenetically regulates gene expression to inhibit cell proliferation and induce apoptosis as the colonocytes exfoliate into the lumen. Alveolar hemorrhage: an underdiagnosed complication of treatment with glycoprotein IIb/IIIa inhibitors. Analysis of the Ter349Glu rhodopsin knock-in mouse showed a rapid, early onset degeneration in homozygotes with a loss of proper rod outer segment development and improper disc formation.

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Recent advances in the management of prostate cancer have shown considerable development with time and many novel therapeutic agents have been approved over the past years. Symptom production on tobacco and tomato is determined by two distinct domains of the satellite RNA of cucumber mosaic virus (strain Y).

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Expression of the Rho-GEF Pbl/ECT2 is regulated by the UBE3A E3 ubiquitin ligase. In Arabidopsis thaliana the MgHb promoter, linked to a beta-glucuronidase coding region, directed expression in the vascular tissue, in shoot meristem and at root branch point--a pattern very similar to the combined expression pattern of the two non-symbiotic A. After two weeks of exposure of virus and cells to CRDS, there is complete inhibition of virus replication. Outbreak of cutaneous dermatophytosis in the Judo French Programme in Orleans: September 2004-June 2005 However, because growth rate in a chemostat is set by the experimenter, it seems impossible to employ the chemostat to study the control of microbial growth by processes within the microorganism.

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Medication errors in anaesthetic practice: a report of two cases and review of the literature. Gel mobility shift and chemical modification data suggest that these cysteine residues do not form intra-molecular disulfide linkages as a structural feature of 2Apro.

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For the symmetric MDM-ENA, it has been shown that a FR can be excited by the normally incident light. Additionally, we investigated whether the predictive model created can be applied to data from the subsequent flu season.