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We found that FOXM1 upregulates its own transcription and its protein stability depends on its interaction with the chaperone nucleophosmin. A hemispherical energy analyzer was constructed by using a novel approach to control the fringing electrostatic field. Low-molecular-weight polyethylenimine enhanced gene transfer by cationic cholesterol-based nanoparticle vector.

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Effects of intracerebral estradiol on the dorsal immobility response in the rat. Portions of these apparatuses could be aseptically removed for examination by scanning electron microscopy, or for the determination of the number of viable adherent L pneumophila. cDNAs for rodent P(1)450, P(3)450, and P450a were expressed in the modified vaccinia virus-T7 RNA polymerase system. Exercise, sedentary pastimes, and cognitive performance in healthy older adults. A patient is described with myoclonic dystonia, a disorder characterized by a combination of dystonia and myoclonic contractions.

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From the DCR spectrum of different groups, it is clear that DCR behaviour is different in the frequency range from 0.3-1.5 MHz, under similar conditions of temperature, conductivity and concentration of erythrocyte suspension and strength of applied AC field. Smears from 11 tongue squamous cell carcinoma patients were processed by liquid-based cytology, stained via the Papanicolaou method and divided into multiple specimens by cell transfer. A rapid and strong increase of plasminogen activator induced by experimental anaphylaxis in rabbits. Making the connection: randomized controlled trial of social skills at school for children with autism spectrum disorders. Variant subcellular targeting of Nef suggests the existence of multiple activities of Nef within HIV-infected cells.

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Compare the sensitivity and specificity of Snyder test (ST), lactobacillus count (LBC) and Cariostat in mixed dentition children with and without caries. The diagnosis of depression is often dependent on somatic symptoms which overlap with the symptoms of many medical illnesses. A monolayer of rat PMVEC model was constructed by culturing a cell suspension on transwell filter or polycarbonate filter membrane.

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Therefore, we tested the hypothesis that diet influences bacterial metabolism by measuring short-chain fatty acids (SCFAs) in stool samples from very-low-birth-weight (VLBW) preterm infants without GI disorder as surrogate biomarkers of bacterial metabolism. In this series, the problems of surgical treatment for cardiac myxoma and associated lesions are also discussed. Physiological characteristics of dysphagia following thermal burn injury. It is possible to deliver tidal volumes accurately and eliminate several hazards associated with the low pressure system and oxygen flush. Studies of house painters revealed that exposure to different types of paints had an effect on transferrin.

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Effects of different simulated gravity conditions on neuromuscular control in drop jump exercises. This article describes the potentials and challenges of quantitative analyses of human neonatal brain images using structural magnetic resonance (MR) imaging and diffusion tensor imaging. A search of mosquito vector and Drosophila sequences at available databases revealed the presence of putative Lamr/p40 proteins with high homology to the Lamr/p40 from shrimp.

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The palisade tympanoplasties-technique with using of tragal and conchal autografts for reconstruction of the tympanic membrane and the auditory canal wall was described. Microleakage of composite restorations bonded with three new dentin bonding agents.

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A retrospective analysis of the medical records of 105 lung cancer patients who were admitted to the ICU between January 2008 and January 2011 was performed. DNA minor-groove binders: results and design of new antitumor agents. Tardive dyskinesia (TD), a serious complications of neuroleptic chronic use, has no effective therapy yet. Starting from a hit with low micromolar binding activity, we report here the main steps of the optimization process leading to the identification of the preclinical candidate SAR216471.

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The annotated results along with the server can be accessed at http://bioinfo.mc.vanderbilt.edu/CNVannotator/. To investigate the attitudes of final year veterinary students towards small animal dentistry and to examine the teaching received in this subject, both at university and during extra-mural studies. Finally, the Golgi/EM procedure was used to study the differentiation and developmental plasticity of hippocampal and dentate neurons in transplants and slice cultures of hippocampus.

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No evidence of benefit for universal screening with 75 g oral glucose tolerance test in polycystic ovary syndrome. However, this approach is associated with often severe climacteric side effects and fibroids quickly relapse after treatment cessation. Therefore, in the absence of stromal aromatase gene expression, epithelial proliferation, leading to prostatic hypertrophy and hyperplasia, may result from a combination of androgenic stimulation of proliferation and failed activation of ERbeta by locally synthesized estrogens.

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This was a retrospective study including a total of 16 patients with advanced urothelial carcinoma who showed evidence of progressive and/or recurrent disease after first-line therapy with GC and subsequently received second-line chemotherapy consisting of paclitaxel (175 mg/m(2)) and carboplatin (area under the curve 5). The development of portal or hepatic venous thromboses after RFA in patients with HCC is rare and usually is associated with favorable prognoses. The application of high power ultrasound for dehydration of porous materials may be very effective in processes in which heat-sensitive materials such as foodstuffs have to be treated. The strength of effective connectivity determined in this manner was higher throughout the trial in the posterior parietal cortex than the dorsolateral prefrontal cortex.

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Influence of racket polar moment on joint loads during tennis forehand drive. In the best model, the carboxyl terminus of secretin was found to bind in a groove above the beta-hairpin region of the receptor amino terminus, with its amino-terminal end adjacent to the third extracellular loop and top of transmembrane segment VI.

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Effects of low-protein diet on mRNA for ECM components, MMPs and TIMPs in glomeruli of focal glomerular sclerosis. Evidence is presented for a differential effect of trypsin on both phases. Effects of metal ions and an inhibitor on the fluorescence and activity of acutolysin A from Agkistrodon acutus venom.

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The TGF-alpha mRNA level increased when the cell cultures were allowed to incubate in their conditioned medium for 3 days, suggesting that a secretory product from the cultured cells is capable of stimulating the accumulation of the TGF-alpha mRNA. What should primary care providers know about pediatric skin conditions? DLX5 expression was restricted to few cells in the vestibular aspect of the dental epithelium, while DLX5 mRNA signal was more widely distributed in dental mesenchyme.

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Deciphering the molecular mechanism of pH-dependent refolding and membrane insertion of the T-domain, which is considered to be a paradigm for cell entry of other bacterial toxins, reveals general physicochemical principles underlying membrane protein assembly and signaling on membrane interfaces. The basic design of experiments and optical and imaging components is discussed to create a microscope that is capable of monitoring dynamic molecular associations in living cells.

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Both SAE and DL are safe and offer similar therapeutic laparotomy rates. Differences between skin test results before and after treatment when retesting only strong reactors are caused by a combination of effects that are difficult to distinguish. A sizeable proportion of patients with angina, angiographically smooth coronary arteries and positive exercise test (syndrome X) have stress/rest myocardial perfusion defects. Does more equitable governance lead to more equitable health care?

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Adjacent-segment ROM increases and posterior disc height decreases over time were greater with the hybrid configuration. Findings were then synthesized using a narrative thematic approach to identify and categorize relevant needs into thematic categories and subcategories. Applications of stem cells in interdisciplinary dentistry and beyond: an overview. The odds ratio (OR) calculated by logistic regression was the measure of association used. Estimating the physical cluster-size distribution within materials using atom-probe.

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Brains from AIDS patients with an HIV-induced encephalopathy but without opportunistic infections or indications for an inflammation were studied by immuno- and enzyme-histochemical methods. Patients may be at increased risk for severe sinus node depression when diltiazem is administered during enflurane anesthesia.

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This increase in BG might be correlated with postsurgical complications. We describe a method to increase arterial oxygenation and to ensure stability of O2 and CO2 during carbogen breathing in patients with malignant disease. To address this, we mapped ASD and ID risk genes onto coexpression networks representing developmental trajectories and transcriptional profiles representing fetal and adult cortical laminae.

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Pulse-wave morphology and pulse-wave velocity in healthy human volunteers: examination conditions. The utility of an in-hospital observation period after discontinuing intravenous antibiotics. The data from this programme can be used as a reference to environmental data acquired near pollution sources, and as a basis for measures against e.g. Expression of fetal-type genes, such as atrial natriuretic factor, was also significantly lower in Tg-Y319F than in Tg-WT mice.

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Ultrastructurally, the organism had a eukaryotic nucleus and three cell-wall layers. Novel ultra-low temperature co-fired microwave dielectric ceramic at 400 degrees and its chemical compatibility with base metal. An H275Y mutation was detected in the neuraminidase gene sequence. Intracranial pressure (ICP) was controlled with mechanical hyperventilation, mannitol osmotherapy, pentobarbital, and surgical decompression.

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For this purpose, 12,800 people were studied from the 1995 and 1997 Spanish national health surveys to estimate the percentage of less-than-good and less-than-fair health for each educational level. Nonviral gene vectors from synthetic catiomers (polyplexes) are a promising alternative to viral vectors. By using the Euler-Lagrange variation, we derive a system of three coupled governing equations, i.e., the generalized Poisson-Boltzmann equation for the electrostatic potential, the generalized Laplace-Beltrami equation for the solvent-solute boundary, and the Kohn-Sham equations for the electronic structure. Experimental evidence collected over the last 45 years by a number of investigators supports a link between cooperativity and slow conformational reorganizations of the glucokinase scaffold.

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Dynamics of indices of sympatho-adrenal system at application of a combined central sedation using alpha2a-NMDA and phentanyl Thus, only the caudal half cells are committed to give rise to the vertebral pedicle, and only the rostral half cells are committed to give rise to the fibrocartilage of the intervertebral disk.

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The etiopathogenesis of microtia is still unknown in the majority of the cases, particularly for individuals presenting with isolated microtia. The groups were compared according to age, gender, degree of fracture displacement and clinical signs.

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The deposits are studied using scanning electron microscopy, adsorption of nitrogen, and adsorption of water through attenuated total reflection-infrared spectroscopy. We present the case of a palliative care consult conducted across language barriers to frame a discussion about the use of interpreters for family meetings, including the evidence for using a professional interpreter, the burden experienced by interpreters involved in end-of-life discussions, potential challenges encountered when conducting a family meeting with an interpreter, and recommended best practices for interpreter use in these settings.

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Early maladaptive schemas (EMSs) are hypothesized to be stable, trait-like, enduring beliefs underlying chronic and recurrent psychological disorders. XIAP binds copper ions directly at one or more unspecified sites, indicating that the protein may function as a copper sensor.

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In addition, as documented here, in mutant variants of the transporter, inhibitors of the wild-type ABCG2 may become actively transported substrates. Self-organization of chaos synchronization and pattern formation in coupled chaotic oscillators.

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The dimer showed the highest electrophoretic mobility in the alkaline zone of the pH. Research indicates that nurses are not well prepared to care for patients with pain. Reversed-phase high-performance liquid chromatography-tandem mass spectrometry was used to analyze seven urinary phthalate metabolites. Identification of 123 previously unreported mutations in the F8 gene of Iranian patients with haemophilia A.

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Selection of distinct Valpha/beta T-cell receptor families during in vivo and in vitro T-cell maturation. Progress in charge transfer systems utilizing porphyrin donors and simple aromatic diimide acceptor units. Toxoplasma gondii is a common pathogen in patients with acquired immune deficiency syndrome (AIDS). Right upper lobectomy and dissection of lymph nodes were performed as second operation. BITA use in the elderly is associated with an increased risk of sternal wound infection.

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The risk of autistic features is increased in children with inborn errors of metabolism, especially in the presence of cognitive and behavioral deficits. The major tumour types arising in individuals with NF1 include neurofibromas, malignant peripheral nerve sheath tumours, and gliomas, whereas NF2 is characterized by the formation of schwannomas, meningiomas, and ependymomas. Other clinical findings were cataract, pigmentary retinopathy, and peripheral neuropathy. The number of fully trained and employed CTs in these 15 European countries varied from 35 to 2600.

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Current use of estrogen appears to decrease the risk for fracture in older women. Between July 1990 and September 1991, demineralized perforated allogeneic bone implants (Pacific Coast Tissue Bank, Los Angeles, CA) were placed in 72 patients. Follow-up radiographs and ultrasonographies of the five hips showed normal joint anatomy.

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By contrast, SAXS data at low values of r suggest that there are no significant conformational changes of the protein moiety itself after PEGylation The location of the PEGylation site within the conjugate was identified, and found to be consistent with expectation from the conjugation chemistry. These advances in both imaging and genomics contribute to more personalized and predictive patient management. Morphometric analyses of 100 skulls were conducted using CT scans and BrainLab. adrenal glands and gonads), and expression of this factor is tightly regulated in a tissue and cell type-specific manner.